Psychrophiles, literally “cold lovers,” are organisms adapted to live at extremely cold temperatures. These are single-celled life forms, most often bacteria, but also blue green algae, yeasts, and fungi that can grow at temperatures as low as -13 degrees. A mesophile is an organism that grows best in moderate temperature, neither too hot nor too cold, typically between 20 and 45 °C. The term is mainly applied to microorganisms. Psychrophiles are extremophilic bacteria or archaea which are cold-loving having an optimal temperature for growth at about 15°C or lower, a maximal temperature for growth at about 20°C and a minimal temperature for growth at 0°C or lower. Microorganisms are classified into three primary groups on the basis of their preferred range of temperature: psychrophiles (cold-loving microbes), mesophiles (moderate-temperature-loving microbes), and thermophiles (heat-loving microbes).
A mesophile is an organism that grows best in moderate temperature, neither too hot nor too cold, typically between 20 and 45°C. The term is mainly applied to microorganisms. Mesophiles are microorganisms which grow at moderate temperatures between 20 °C and 45 °C and with an optimum growth temperature in the range of 30–39 °C. They are isolated in both soil and water environments; species are found in the Bacteria, Eukarya, and Archaea kingdom. Thermophiles are those organisms which grow above 40°C, and which have optimal growth temperatures between 50 and 55°C. One group of thermophiles the PTS have been described above, and so will not be dealt with here; thermophilic thermoduric organisms have been mentioned immediately above. Thermophiles are heat-loving, with an optimum growth temperature of 50o or more, a maximum of up to 70oC or more, and a minimum of about 20oC. Bacteria are happiest when it is warm, and it will multiply the quickest between 20°C and 50°C. The optimum temperature for bacteria growth is 37°C the same temperature as the human body.Bacteria grow most rapidly in the range of temperatures between 40° and 140°F, doubling in number in as little as 20 minutes. This range of temperatures is often the "Danger Zone." Organisms that prefer cold environments are termed psychrophilic, those preferring warmer temperatures are termed thermophilic and those thriving in extremely hot environments are hyperthermophilic.