Which software is better for Protein-Protein and Ligand - protein docking?

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Anu Manhas

Hi..

Autodock (Protein-ligand) and Hex or Haddock (protein-protein)

Please look into the link, you will get a list

http://www.geneinfinity.org/sp/sp_structdocking.html

Regards

Anu

Mokhtar Nosrati

Protein-ligand------Autodock

Protein-protein-----Hex or Cluspro

Prateek Kumar

I have used Schrodinger and AutoDock (& Vina) and found both are reliable. As schrodinger is a commercial license based tool while AutoDock (& Vina) are freely available. Schrodinger generates a bit amount of data that can be more useful in the study.

I haven't used Discovery Studio but as I read in literature that is also good.

Mohsin Yousuf Lone

Please go through this link:

http://click2drug.org/

Ganesh Sekaran

Thank you for your comments. @ Prateek. I have tried with Autodock but some error following the manual and not clear, can you provide me a Autodock methodology please.

Hello Sir,

Sorry for the late response. I have attached the file of methodology to run autodock. Please find the same.

Sargol Mazraedoost

Hello

CASTp, Autodock vina, Swissmodel, Qsite, Chimera, RasMol or JMOL, MOE, BIOVIA Discovery Studio.

Check in these links. It might help you.

https://www.click2drug.org/

Good Luck.

Turgut şekerler

i use chimera for protein ligand, aoutodock embedded in vina. It is very useful and easy, moreover, it is free. But shrodinger is quite popular if you are considering buying it.