In literature there are different methods to detect hpv on bladder tumour studies. Frozen sections, direct tumour tissue, urine, cytology. Using PCR assay I'm planning a study on bladder tumour & hpv. Which sampling method do you recommend?
Because of the nature of HPV (epitheliotrophic and local infection), you can find the HPV DNA from direct sampling of tumour tissue by PCR assay. The stability of DNA let you detect the HPV DNA from frozen (at -20 degree) or paraffined sample.