Which medium is good for large scale production of monclonal antibodies, IMDM, DMEM or RPMI..???

Kulandaivelu Karikalan @Kulandaivelu_Karikalan

01 January 1970 0 6K Report

we were using IMDM to cultivate the hybridoma cells and produced good quality of monolconal antibodies... at present we have been cultivating the cells using RPMI medium and not getting good output... cell division, viability and antibody production rate is decreased... is this the problem with the medium...? we have tested FCS with IMDM and it was fine....

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