The RoB 2 tool assesses the risk of bias in randomized clinical trials and the ROBINS 1 tool in non-randomized studies of interventions, such as cohort studies, case-controls and non-randomized clinical trials. But my question is, if there are clinical trials and cohort studies that do not have a control group, can the ROBINS 1 tool be applied? Or is there a more suitable tool?
Thank you.