Articles addressing PCO rates amongst singlepiece and 3-piece IOLs shares different opinion and so I want an answer as per your personal experience.
I want opinion for SIMILAR TYPE of IOL optic design. i.e you can compare ALCON 3 piece vs ALCON Single piece, OR Tecnis 3 piece vs Tecnis Single piece..like that.
In my opinion, lower PCO rates are associated with quadrangular and hydrophobic haptics. Three pieces IOLs have no edge, so have higher PCO rates.
Lower PCO rate has been associated with the presence of posterior square edges. Studies have shown that shrink wrapping of the capsular bag around the IOL optic is an important mechanism to prevent PCO and in theory 3 piece IOL may have better outcomes regarding this complication however no randomised trials have been performed to confirm this theory. In addition 3 piece IOL are much less used nowadays which make it more difficult to perform studies to compare both IOL's.
are you asking for PCO rates for 3-piece IOL for sulcus or in-the-bag IOL placement?
The truncated, square edge of the IOLs causes a blockage of epithelial cells at the optic edge, preventing ingrowth over the posterior capsule. So I believe it is an issue of the design of a particular IOL that is used (whether it is 3 or 1-piece)
Please also check:
Br J Ophthalmol. 2013 Jan;97(1):18-22. doi: 10.1136/bjophthalmol-2012-301899. Epub 2012 Sep 5.
Comparison of posterior capsule opacification between a 1-piece and a 3-piece microincision intraocular lens.
Prinz A1, Vecsei-Marlovits PV, Sonderhof D, Irsigler P, Findl O, Weingessel B.
What i meant is when there is same OPTIC design with difference JUST IN HAPTICS, which IOL has more PCO rates.?
(For example, you can compare ALCON, SENSAR or TECNIS 3 piecce vs singlepiece IOLs)
As per following article, SINGLEPIECE may have more PCO rates than 3 PIECE with same OPTICS.
Please go through following:
https://bjo.bmj.com/content/bjophthalmol/88/6/728.full.pdf
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