These are the critical molecular factors that take part in Hatching Embryo,
Molecular Factors
TEA DNA- binding domain, these factors bind to the consensus TEA/ATTS cognate binding site[16]
TEF-3 - renamed Tead1 and Tead4
Tead3 - is expressed in the placental syncytiotrophoblasts
E-cadherin - Calcium ion-dependent cell adhesion molecule, a cell membrane adhesive protein required for morula compaction
epithin - A type II transmembrane serine protease, identified in mouse for compaction of the morula during preimplantation embryonic development. Expressed from 8-cell stage at blastomere contacts and co-localises in the morula with E-cadherin. PMID: 15848395
Na, K-adenosine triphosphatase - A sodium potassium pump that generates an osmotic gradient for fluid flow into the blastocoel
Zonula occludens-1 - (ZO-1) Tight junction protein involved in morula to blastocyst transformation in the mouse PMID: 18423437