Which force field is better for protein simulation among CHARMM & AMBER?

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Ke Li

Amber is better for protein simulation

Abdul Basit

There are different forcefields for proteins and drugs. Latest forcefields are better in general.

Kauê Santana

Hello Syeda,

It is really difficult to compare the performance of different force fields applied in the study of proteins. Different force fields may have different results, but not necessarily the results obtained with one will be better than those obtained by the others. Here are some commonly applied force fields:

GROMMOS

CHARMM

OPLS-AA

Amber

Syeda Rahimon Naher

Ke Li ; Abdul Basit & Kauê Santana

Assalam o alaikum wa rahmatullahi wa barkatuhu

Thanks a lot for your kind words. Wish you all the best.

Regards