I want to minimize the value of one variable which depends directly on four variables and indirectly on three variables.

I need to adjust the parameters from a machine (establised manually) to reduce the efect in "response" variable. Also, I have other variables which I can't choose their values.

I have at least 5000 observations which given some independent variables and the machine parameters established I have the response variable value.

I think in linear programming but I don't have an objective function and constraints but I want to minimize efects. Also I think in DOA and Taguchi but I dont have to do and experiment, I have 5000 experimients really done.

I will appreciate your responses! Thanks

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