Which diabetes-related target proteins should I use for an in silico study of a medicinal plant's antidiabetic potential?

More Abdelhak Maghchiche's questions See All

What are the best practices to combat water scarcity in arid and semi-arid regions?

Water scarcity is a significant issue in arid and semi-arid regions due to limited rainfall and high evaporation rates. To address this challenge, various strategies and practices have been...

28 July 2024 7,611 2 View

What are the best innovative materials for harvesting water in arid and semi-arid regions?

Water scarcity in arid and semi-arid regions necessitates the development of innovative solutions for water harvesting. Researchers and engineers have been exploring various advanced materials...

28 July 2024 594 6 View

Can Biosensors Be Utilized for Drug Prediction from Plants?

Can biosensors be used in drug prediction and discovery from natural plants?

22 May 2024 9,639 0 View

I need the identification of this plant ?

I need the identification of this plant. Additionally, is there any extraction method employed to identify its bioactive compounds?

01 March 2024 2,488 6 View

Simulating Triaxial CD Test on Sand using Abaqus: Seeking Advice on Constitutive Laws and Parameter Determination?

I am currently engaged in a project where I aim to simulate a triaxial compression test (CD test) on sand using the Abaqus finite element software. My goal is to accurately model the behavior of...

06 January 2024 4,656 0 View

What methods or strategies can be employed to reduce the toxicity of nanoparticles in the field of biomedicine?

What strategies can be employed to mitigate nanoparticle toxicity in the context of wound healing?

30 December 2023 2,654 1 View

How to use a material studio to build a Montmorillonite( bentonite ) model?

how to use a material studio to build a Montmorillonite ( bentonite ) model? with any exchangeable ion, like Na+, K+, Fe3+ etc. and thank u

03 September 2023 2,435 1 View

Is it acceptable to employ hacked version of high-score software for x-ray data analysis purposes?

Is it ethical (legally allowed) to publish X-ray diffraction spectra in a scholarly article if the data analysis was performed using an hacked version of High-score software?

25 April 2023 584 3 View

Energie and dose deposite?

Hello everyone i am using Gate to simulate an electron Beam toward a water cube , and i want to have information about deposition of energy in the cube . so i used the option Dose Actor. but i...

23 April 2023 3,327 0 View

Can ChatGPT robot contribute to chemistry research like discovery of new drugs and the prediction of practical experiments results ?

02 February 2023 2,119 3 View

What precautions should be taken while handling S. aureus enterotoxin Type B in the lab?

I would like to understand potential safety concerns while handling SEB in the lab. Especially while working in animal house facility. Would like to know precautions for handling. Sigma MSDS...

07 August 2024 6,034 3 View

Why does my protein refolded to beta sheet during thermal denaturation analysis?

Hi! So i attempted to understand a novel protein behavior towards heat application by analyzing its secondary structure change. I subjected the protein to a thermal denaturation analysis using...

06 August 2024 1,989 3 View

How to understand this crystallographic phenomenon of low temperature crystals in zeolite?

During low-temperature testing, new diffraction peaks that appear could be indicative of several phenomena. In one of our tests, we observed notable new peaks around 40° and 45° in a specific...

06 August 2024 726 3 View

Transfection in HEK293T cells?

Dear All, I am trying to transfect a pCDNA3.1 vector containing my gene of interest. The purpose is to figure out the localization of the protein of interest. I have fused the protein with GFP on...

31 July 2024 9,892 4 View

How to retain the a GFP tagged gene expression in stable cell line?

Hello , I established a stable cell line expressing GFP tagged to a centrosomal gene having G418 drug selection marker. I validated the stable line by IFA and Western blotting, results are fine....

29 July 2024 5,007 0 View

Do some Staphylococcus aureus strains have in vitro antimycobacterial activity ?

Some Staphylococcus aureus strains Inhibit the growth of Mycobacteria in Mueller Hinton Agar medium containing 10% OADC. Do some Staphylococcus aureus strains have in vitro antimycobacterial activity?

29 July 2024 10,023 2 View

What is the relationship between protein structure and N or C terminal tagging choosing?

I want to do 2,3-butanediol dehydrogenase(BDH) enzyme purification to confirm its activity for 2,3-butanediol. Before that, I need to confirm which N or C terminal tagging is better for enzyme...

28 July 2024 366 3 View

Why cannot i find my protein on cell surface after antibiotic selection of expressing plasmid?

I cannot confirm cell surface protein expression by flow cytometry even after transfection and antibiotic selection of cells. Does it take long for proteins to express on the cell surface? the...

28 July 2024 3,178 3 View

EDC carbodiimide and NHS easter 's half life among different pH?

It has been long known that EDC carbodiimide and NHS easter's half life agains hydrolysis are highly related to pH. However, very surprisingly, not yet found a paper giving a table/chart of their...

25 July 2024 8,738 0 View

Does post-translational protein modification cause devisions on observed pI verses calculated pI?

In running two-dimensional gel electrophoresis on bacterial protein, some spots that appear to match a protein sequence have a significantly more acidic isoelectric point than the calculated pI....

24 July 2024 8,076 3 View