I would like to go for a secondary metabilite screening among leaf spot fungi especially for anticancer activity other than taxol. Someone please suggest an economically important secondary metabolite which I should screen for.
Dear Ramani,
The following recent review article lists a number of fungal secondary metabolites including the well-known compounds such as paclitaxel (also known as taxol) (Stierle et al., 1993), podophyllotoxin (Eyberger et al., 2006; Puri et al., 2006), deoxypodophyllotoxin (Kusari et al., 2009a), camptothecin, and structural analogs (Puri et al., 2005; Kusari et al., 2009c, 2011; Shweta et al., 2010), hypericin and emodin (Kusari et al., 2008, 2009b), and azadirachtin (Kusari et al., 2012).
For more on this topic, please see the review article contained in the following link:
http://journal.frontiersin.org/article/10.3389/fmicb.2016.00906/full
Hoping this will be helpful,
Rafik
Dear Ramani,
Here attached four reviews that could provide you with some ideas.
Best regards
Robert
Thank you very much Rafik for the info you shared with us on this 2016 review on endophytic fungi. It is very interesting!
Robert
You are welcome.
I wish you a lot of success in your interesting project.
Rafik
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