Dear Dr. Ghasemi,

I got curious and I'm willing to know which chemical reaction you will use for your AB conjugation?

If you're going to use Thiol/Maleimide reaction by introducing a terminal Cys, what your plan for site-specificity of the conjugation to AB would be? Because, as far as I know, there are Cys residues in the variable chains of ABs as well. I will really appreciate your response.

Thanks so much in advance

and best regards,

Farzad.

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