Which is a lucid standard comprehensive book to guide on psychological scale construction and its standardization?

02 March 2021 7,082 3 View

What test should I use to compare two or three means, if data is not normally distributed but sample size is > 30 in each group?

I personally feel this as a most confusing question. As per my understanding, if sample size is > 30, and sample is skewed, we can still use paramteric approach, as it will follow Z...

01 March 2021 1,587 6 View

How to calculate Ligand-active site distance in a ligand-protein complex from MD simulation?

I have run a MD simulation of a ligand-protein complex in GROMACS using CHARMM forcefield. Reviewer has asked me to calculate Ligand-activesite distance and binding free energy of ligand with...

27 February 2021 4,703 1 View

Efficiency of Proximity Feed Patch Antenna ?

Greetings to all of You! I have searched some research papers for the designing of a proximity coupled patch antenna. Researchers are talking about the impedance bandwidth of the antenna but...

24 February 2021 7,662 3 View

Please help in identification of this insect?

This insect is minute in size around 1 mm and not clearly visible with naked eye.

22 February 2021 5,907 11 View

What is causing the raw fluorescence to be negative?

Hi everyone, I would really appreciate it if someone can tell me when and why a raw fluorescence starts below zero. In the picture attached below the blue colour curve starts from a negative...

09 February 2021 4,642 3 View

How to match the XRD of a compound for which there is no JCPDS file ? Is there any other characterization to claim the synthesis of desired compound?

I have synthesized LiMgF3 using the starting precursors LiF and MgF2 via solid state diffusion method. Now I am looking for some characterization to claim the desired product, as there is no...

09 February 2021 921 3 View

Can anyone suggest me broad host range fluorescence expression vectors for Gram-positive bacteria ?

Hi everyone, I am looking for fluorescence expression vectors for expression in gram-positive bacteria present in the skin microbiome. I need to tag them with a fluorescence marker and observe...

06 February 2021 2,566 4 View

Are the hyperspectral image datasets which are publicly available at ehu.eus website atmospherically and geometrically correct?

I've come across a couple of publicly available hyperspectral image datasets from the website http://www.ehu.eus/ccwintco/index.php/Hyperspectral_Remote_Sensing_Scenes Now, my concern is...

05 February 2021 3,550 1 View

Any recommendations for open-source survey form builder, which has option for semantic differential scale questions apart from Likert scale?

Asking this as Google forms doesn't allow multiple items in a semantic differential format.

04 February 2021 5,869 4 View

What is the difference between genotype and haplotype data in the ped format?

Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...

27 February 2021 1,965 1 View

What's the name of important packages for R that generate analysis with mtDNA?

I have mitochondrial DNA sequences to perform analysis of the genetic diversity and population structure of a fish species. What packages can I use on R? I estimate that I need to generate...

01 October 2020 862 5 View

I want to classification haplotype data by CNN. Can you introduce a suitable network?

hi everybody I converted each word into a vector with one-hot encoding. So that each haplotype has become a two-dimensional matrix. I need CNN to classify them. I appreciate your help. Best regards

25 July 2020 322 2 View

How to correctly choose population strata and interpret results for the detection of loci under selection from RADseq data using Bayescan?

I am working on the analysis of fungal populations sampled from 12 geographic locations using RADseq data. The dataset contains 7439 polymorphic loci with ~10 snps per RAD locus (75,482 snps...

19 May 2020 643 3 View

Which method most suitable for calculating similarity and genetic distance?

Hi everybody I want to calculate the genetic distance and similarity for ancestral populations. My data is haplotypes. I appreciate your help. Best regards

03 March 2020 8,142 10 View

How To Convert Snp haplotype Data Into 0,1 Matrix? Which software or package is better?

Hi everybody I want to convert HapMap Snp haplotype Data Into 0,1 Matrix so that I can use it in other works. I appreciate your help. Best regards

11 December 2019 414 3 View

How To Convert Snp haplotype Data Into 0,1 Matrix? Which software or package is better?

Hi everybody I want to convert HapMap Snp haplotype Data Into 0,1 Matrix so that I can use it in other works. I appreciate your help. Best regards

02 December 2019 3,312 4 View

How to convert haplotype combinations to data for asssociation study?

Hello all, from 2k SNP dataset I got some 300 haplotype block having 2 to 3 SNPs in each. Can anyone help in conversion of these haplo combinations to data for association study?

10 November 2019 5,980 3 View

How to calculate Rh haplotype frequencies?

I obtained the frequencies of Rh phenotypes in my sample but I would like to calculate the haplotype frequencies. Most of the studies used this reference: : The estimation of gene frequencies in...

06 July 2019 737 2 View

How to do Haplotype-based GWAS?

Hi, I have a SNP dataset containing 717045 SNPs. I want to a GWAS using Haplotype blocks. But I do not know first how to create haplotype SNP dataset for GWAS and also the criteria for creating...

04 May 2019 5,732 4 View