Dear All,
Greetings from IIPL.
Since the start of COVID-19 pandemic, many research work has been published in the public domain which mainly indicates that patients with celiac disease does not have higher risk of COVID-19 as compared to the general population.
But no research paper has been published which throws some light of impact of COVID-19 on people with diagnosed Celiac Disease. This set of people doen't know that they are already in the celiac zone or atleast in the gluten-intolerant zone. Therefore, they may not be under a gluten-free diet. And when these people contract the COVID-19 infection, how their underlying autoimmune celiac disease interact with the infection by SARS-CoV-2 virus?
If anyone has any understanding, please contact me. Thanks.
Regards
Arnab Guha
+91-9611186720
Elli, L., Barisani, D., Vaira, V., Bardella, M. T., Topa, M., Vecchi, M., ... & Roncoroni, L. (2020). How to manage celiac disease and gluten-free diet during the COVID-19 era: proposals from a tertiary referral center in a high-incidence scenario. BMC gastroenterology, 20(1), 1-9.
Siniscalchi, M., Zingone, F., Savarino, E. V., D'Odorico, A., & Ciacci, C. (2020). COVID-19 pandemic perception in adults with celiac disease: an impulse to implement the use of telemedicine. Digestive and Liver Disease, 52(10), 1071-1075.
Elli, L., Scaramella, L., Lombardo, V., Scricciolo, A., Doneda, L., Roncoroni, L., & Vecchi, M. (2020). Refractory celiac disease and COVID-19 outbreak: findings from a high incidence scenario in Northern Italy. Clinics and Research in Hepatology and Gastroenterology, 44(5), e115.
Costantino, A., Topa, M., Roncoroni, L., Doneda, L., Lombardo, V., Stocco, D., ... & Elli, L. (2021). COVID-19 Vaccine: A Survey of Hesitancy in Patients with Celiac Disease. Vaccines, 9(5), 511.
COVID-19 patients with asymptomatic celiac disease maybe a vulnerable population. More studies need to be done. I also recommend to do TTG test w.r.t. celiac test for COVID-19 patients who have been hospitalized with moderate to severe COVID-19 infection, irrespective whether they had done early-interventions or not. Let me know you views.
Celiac Disease - Genetic Autoimmune disease.
Dear Arnab, thank you for asking this interesting technical question. In this context please have a look at the following potentially useful articles which might help you in your analysis:
Risk perception and knowledge of COVID-19 in patients with celiac disease
Article Risk perception and knowledge of COVID-19 in patients with c...
Risk of Severe Covid-19 in Patients with Celiac Disease: A Population-Based Cohort Study
Article Risk of Severe Covid-19 in Patients with Celiac Disease: A P...
Risk of COVID-19 in celiac disease patients
Article Risk of COVID-19 in celiac disease patients
The second article has been posted as public full text on RG. Thus it can be freely downloaded as pdf file. I hope it helps.
Good luck with your work and best wishes!
Patients with Coeliacs are often deficient in various micronutrients. It is important that they are screened for these and if necessary take supplements. This may boost their immune function and reduce the risk of SARS-CoV-2 infection and the severity of COVID-19.
Lebwohl B, Larsson E, Söderling J, Roelstraete B, Murray JA, Green PHR, Ludvigsson JF. Risk of Severe Covid-19 in Patients with Celiac Disease: A Population-Based Cohort Study. Clin Epidemiol. 2021 Feb 18;13:121-130. doi: 10.2147/CLEP.S294391. PMID: 33628059; PMCID: PMC7899312.