Hi Nageeb, unfortunately animal models of diseases dictate that they show the full blown pathology within a year if you are looking to get funded.

An animal model of sporadic AZ might be out there, but it will probably not get funded since they are sporadic and non-reproducible unless you have a large cohort of animals.

I will follow it

Hi Nageeb

Please see table 2 here:

https://content.iospress.com/articles/journal-of-alzheimers-disease/jad170045

And this paper:

Animal Models of the Sporadic Form of Alzheimer's Disease: Focus on the Disease and Not Just the Lesions

Good luck

Boaz