How to create comfa contour map?

Thank you for reading. I'd like to create contour map generated with the CoMFA. If you know how, please tell me the reference paper or books. And is it possible to create it when using other...

31 December 2019 5,746 3 View

What's the constraint condition that oscillation occurs?

I have mathematical problem. I want to know the constraint condition that oscillation occurs (differential equation). For...

04 May 2019 1,318 7 View

How to predict probability of nucleic acid at ambiguous position?

03 April 2019 5,918 3 View

How to predict probability of each class by using continuous variables?

I do not know how to do in the below case in Naive Bayes. I want to predict probability of each class by using continuous variables. In my case, class's name are A,B,C,D and prior probability is...

31 December 2018 6,471 3 View

What should I think about the contradiction of my analysis?

I want to know about the Nonlinear Mixed Effect Model. This is my conducted analysis below. 1. Construct base model. 2. Scatterplot between estimated parameters and covariates. 3. Integrate high...

09 October 2018 4,278 3 View

How can I define model in nlme packages?

I read "Longitudinal two-level model" in http://rpsychologist.com/r-guide-longitudinal-lme-lmer. And I'd like to change the Level1 model a little as...

05 June 2018 3,665 1 View

What should I do in keras package when sample size is smaller than explanatory variables?

I would like to use CNN for regression in keras package (backend theano). I have the training data which has 3-dimension and numbers in each coordinate. And the data also corresponds to certain...

04 May 2018 5,375 2 View

Do you know tha program caluculating the energies of van der waals and electrostatic interaction from PDB(PQR) files??

I read thie article below. :Comparative Molecular Field Analysis (CoMFA). 1. Effect of Shape on Binding of Steroids to Carrier Proteins I have PDB files (also PQR) and I'd like to do CoMFA to PDB...

04 May 2018 4,593 0 View

How to use Delaunay triangulation for proteins?

I read the article "Prediction of HIV drug resistance from genotype with encoded three-dimensional protein...

03 April 2018 8,171 1 View

How to change protein structure to constant-size vector?

I have many pdb files (amino sequences are alike). And I would like to use these data for machine learning. In my problem, amino sequences have same length, but the number of atoms is not...

03 April 2018 1,527 3 View

Buffer Exchange using column packed with sephadex G-25 effect on protein concentration?

Hello, If i am doing a buffer exchange for an antibody of 1mg/mL, does the elution lose protein in the process of buffer exchange? For example, if i flow through 500 uL of 1mg/mL sample, and...

03 March 2021 6,299 3 View

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03 March 2021 5,360 2 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

Timeout error!! Processor in the loop (PIL) using STM32F4 Matlab 2018a?

Dear Researchers I am trying to perform a PIL simulation using STM32F4 Discovery board and comunication serial USB TO TTL. During simulation I receive the following timeout error: An error...

01 March 2021 2,327 1 View

How can we raise the figure when we writing a paper with Latex ?

Hi, everyone. I'm a starter to write a paper by Latex. But I have some difficulty using it. I'm writing the paper with 2 columns. And, there is one figure that occupies the 2 both-sides. I want to...

26 February 2021 3,738 3 View

What is the best way to calculate the angles of twist for concrete columns subjected to torsional moment using finite element software?

In Finite element software like ANSYS , there is difficulty in obtaining direct results of twisting of concrete members because SOLID65 which is the unique element designed to represent concrete...

26 February 2021 3,806 2 View

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I am trying to find how to know the density needed for a pva electrospinning in a 0.6mm neddle, the electrospinning will be from top to bottom and the problem I really have is the solution because...

25 February 2021 2,615 3 View

Compute for the total volume of concrete needed for the concrete pouring of the foundation including its column up to NGL only as shown in the plan?

Looking for the quantity of cement, sand, and gravel of footings and columns. Thank you!

25 February 2021 3,092 2 View

No amplification data for qPCR on MxPro?

I have set up a qPCR run on MxPro with SYBR green and ROX as a reference, however, when I go to the analysis section the program seems to only collect data for the dissociation curves and not the...

25 February 2021 8,039 1 View

Can I use TCA instead of TFA for protein analyis in RP-HPLC?

I am trying to analyze lipase using the reverse phase-HPLC C18 column. In the literature, 0.1 % TFA was and 60% ACN was used. Can I use TCA in place of TFA? If any other methods are available to...

25 February 2021 2,388 3 View