Does stratified randomization for diabetic patients based on HbA1c values (above 7 and less than 7%) mean that we will enroll one patient with uncontrolled hyperglycemia in the control group and one in the intervention group and so on?
Or it means that we must separate patients into 2 groups based on HbA1c value (for example those with uncontrolled hyperglycemia receive treatment and those with controlled hyperglycemia receive the placebo)??
Stratified randomization refers to the situation in which your target population is divided into strata and randomization or probability sampling technique is performed separately within each stratum to select the sample
Thank you dear Olaolorunpo Olorunfemi for answer
but please what do you mean by probability sampling technique is performed separately within each stratum to select the sample (can you explain by example?)
I guess that the answer to your question is related to which type of research you're designing. If it is a clinical trial and you want to check the response of one drug, I think that you're second alternative is the best. But if you're working in one randomized study to find some shreds of evidence or epidemiological information regards your disease, maybe your first alternative it'll the best option.
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