If a drug's 100mg is safe for human, so what amount of drug or dose safe for experimental animals like, mice, rats, rabbits or dogs. For various experiment, we have to work with new drugs on experimental animals, then it sometimes difficult to select the dose for a particular experiment. I know the in vivo LD50 and in vitro LC50 methods. I just want to know the ratio between human and other animals and also the references.
Dear Dr Robert,
Do you know the exact reference (book or article) from which this table has been derived?
Thanks
Subhash
Dear Subhash,
I think that I obtained this table from the US NCI website.
You should contact my colleague Prof. Véronique Mathieu (she is not registered on RG) at [email protected].
I am sure that she has the full reference.
Best regards
Robert
Interesting question. What is the actual relation between all species?
Dear Subhash,
Here attached are the documents + references.
Best regards
Robert
