I need a good published method that I can cite and use to lysis/destroy cells in saliva. I am not interested in the cells or their contents, just the saliva. I want to be able to use the resulting extract for HPLC analysis.
Since you are interested in saliva, it is not a good idea to lyse cells, since saliva will be contaminated with bacterial proteins, including proteinases, Centrifugation is te way to go (if needed after vortexing, to disrupt aggregates).