29 years old with Type 1 Diabetes Mellitus for over 5 years is on countinous insulin infusion . But for malabsorbtion he has no other problems. He is very keen for any alternative form of treatment for his Diabetes. His wt is 52kg and height is 1.5m
This can be a successful treatment. Without insulin can not be sure, but a lot of advantages.
http://www.paleomedicina.com/hu/a-child-with-type-1-diabetes-mellitus-t1dm-successfully-treated-with-the%20paleolithic-ketogenic-diet-a-19-months-insulin-frredom
Unless he is an exception (e.g. has significant residual insulin secretion measured biochemically), then after five years he will have no significant residual insulin production and will die without exogenous insulin. The treatment suggested above only worked because it was administered in the first few months after diagnosis when there is still residual insulin production (the honeymoon period). To suggest a low carbohydrate diet only in a long duration type 1 diabetic is dangerous and reckless. In the pre-insulin era all type 1 diabetics died.
Besides development of newer therapies like gene therapy ,pancreatic transplants nothing has worked out till now and all are in experimental stages and in animal studies only but premlitidine a pancreatic analogue may work other than a good infusion pump-since allthese transplants be it pancreatic,beta cell transplants none lasts long and viral vectors are being tried for gene therapy to be succesful for this longterm autoimmune process.BESIDES a novel immunomodulator(fingolimod) added to sitgliptin a peptidase4 inhibitor has been studied,also stem cells dendritic cells manipulated exvivo have been tried to maintainthe beta cella remaining and induce their proliferation.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664938/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019244/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573284/
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