I have a research article about these patients that there is not nessecity any laboratory tests even CBC and ESR.
I don`t have any experince about Autologus skin test. but if you do it , what is important and which problem is resolve it?
You need the following exams: CBC, ESR, antibodies anti nucleus (ANA) and extraibles (ENA), antibodies anti thyroid (anti thyreoperossidasis and anti thyreoglobulin), electrophoresis of serum proteins,
The autologous skin test consists in a normal blood sample, then subjected to centrifugation in order to separate the serous part, which is finally re-injected into the patient, with a puncture intradermally in the forearm. The procedure is painless, it takes about 2 hours in total. If wheals appears 30 min after intradermal injection in correspondence of the site of injection (it is shown the mechanism self-reactive urticaria, or autoimmune urticaria) the test is evaluated as positive. For a better yield, it is appropriate that being interrupted therapies that may interfere with the test, in particular anti-histamine drugs or steroids.
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