In my study, the particularities of the POF treatment differed, and depending on the age at which POF appeared. If it happened at the reproductive age, than HRT was preferential, with dosage corresponding to the early follicular phase Estradiol valerate – 2 mg+ progestins. The COC for this group was not most appropriate. The selected progestin depended on the hormonal status and phenotype of the woman. The clinical symptoms of the menopause have disappeared after 3 months of HRT treatment. During following 11 years of treatment there was no case reported on osteoporosis, coronary heart disease, depression, Cr., and other late POF symptoms.
I gine OCP to young women with POF. It does look better for both the pateint & her partner to reach for the "pills" while in older ladies 40-45 and above HRT is appropriate
I prefer HRT with tailored dosage, as this permits the possibility of pregnancy in the unlikely event of recovery. Of course, the patient must be warned that pregnancy is a possibility, and if this is not desired, other methods must be employed.
It remains of concern that I am starting a treatment that will be continued for 20-30 years. This also mandates considerable discussion with the patient.
Regards
CJ van Gerlderen
- Badges
- Science topic
- Similar topics
- Geoscience
- Asia
- India