Problem in energy minimization using Gromacs?

I have done energy minimization of DNA using Gromacs with tutorial lysozyme in water. The potential energy curve show a steep drop.

18 February 2021 4,822 2 View

Is there any software to generate pdb of G quadruplex?

I have a DNA sequence which has predictability to form G quadruplex . I need a software to generate a pdb of it which will form G quadruplex. I am using open Babel but I am not able to set the...

29 January 2021 6,190 4 View

How much Ti and B (in ppm) is required for effective grain refinement and why?

To have the desired grain size in 6061 and 6063 Al alloy, what should be the minimum % of Ti and B pick up and what is the chemistry/metallurgy behind that?

07 January 2021 9,305 2 View

How to make AlV50% alloy by thermit route?

Kindly provide the technical papers/patents on the production of AlV50% alloy by thermit route, by using V2O5

05 January 2021 2,471 3 View

Is there any online webserver for DNA-ligand docking?

I have used Autodock 4.2 for docking studies and trying haddock for DNA-Ligand docking. It shows an error and not supported DNA PDB file. Suggest a template for DNA and ligand PDB file and also...

29 December 2020 1,322 8 View

Apart from deoxidation what are the other applications of Ferro Aluminum (FeAl) and Al wire?

FeAl and Al wire has applications in Steel for deoxidation. I want to know the other application of various grades of FeAl. Does Al wire also has other applications apart from deoxidation? Regards

27 December 2020 8,435 1 View

Is there is any reference if someone is using Ti sponge cored wire instead of FeTi 70% cored wire for plain carbon steel?

There is a different behavior in carbon steel and stainless steel. Drastic low recovery in carbon steel due to high melting temp. But in ss , working temp is high so dissolve at 1668 degree temp....

16 December 2020 8,765 8 View

What could be the possible reason for lack of Mtb protein expression cloned in pET28a even after induction ?

12 December 2020 2,584 8 View

What are the Best practices in NLP dataset preprocessing if the dataset contains plenty of misspelled words?

I am currently working on an NLP experiment. The dataset that I am using is 'Essays' in which there are essays written by participants. These essays contains plenty of misspelled words and...

30 November 2020 5,675 5 View

Why the IT services companies (based in India) are mainly patenting only at the USPTO?

Please suggest some papers/reports on the changes in the policy with respect to patenting of computer software in India. Does it have any implications as to why the IT services companies (mostly...

12 November 2020 8,351 1 View

Is there any chemical safe for sea environment, but could be used for repelling planktons and microorganisms?

As an example of Julia Child, whose first receipe was shark repelent, my team and I are looking for some chemicals which wont harm planktons but will help keep planktons from our robot in sea.

20 December 2020 9,616 4 View

How to start with Principal Component Analysis?

I want to carry out PCA on a set of chemical data, some of them in oxide form and some in elemental form. The oxides are in percentage and the elements are in ppm. I have understood that, the...

14 December 2020 2,201 7 View

How much acid do I need to convert a basic solution into an acidic soluion?

Assuming that there are no chemical buffers present, can anyone confirm that if I want to convert the pH of a basic solution to the pH of an acidic solution then the amount of a monoprotic acid...

27 October 2020 9,156 7 View

Any Book or Article on Pleistocene Planktonic Foraminifera and Calcareous Nannoplankton?

Dear all, I am working on the biostratigraphy of Pleistocene sediments from the high latitude region in south-east Indian ocean sediments. Kindly suggest me any book or articles in which the...

09 September 2020 1,544 9 View

What will we do if foraminifera can used for applied ecological forensics?

We know that Forensic ecology can be used by applied microfossil proxy, called palynology. What do you think and if there is some papers that explain how can investigate the forensic ecology by...

23 July 2020 9,406 1 View

What are the methodologies for sedimentary provenance analysis?

In sedimentary provenance analysis, we use the petrographic methods, geochemistry, heavy mineral analysis, etc. I need the methodology for each technique to determine provenance. if possible then...

11 June 2020 8,530 4 View

Why do you not include geothermal science as a Research Area?

You provide a list of research topics including Geology, Geochemistry and Geophysics. However, many workers in the geothermal field specialise in the integration of the information from the above...

08 June 2020 9,616 4 View

What analytical method is the most adapted to the determination of Rare Earth Elememt-bearing minerals in rock and lateritic soil samples?

I am planning to work on the mineralogy of the rock and lateritic soil samples of the Bingo carbonatite complex in order to determine its REE-bearing minerals and determine its REE prospectivity....

17 May 2020 1,219 18 View

Looking for a book- "Radiocarbon dating practices at ANU" by Gupta and Polach ?

I am looking for a book "Radiocarbon dating practices at ANU" by Gupta and Polach, published in 1985. Can anyone please provide the link or source from where I can get this book? Thank you

13 February 2020 6,525 2 View

How can i analyze heavy metals in urine and HCB, DDE and PCBs in blood samples?

I need exact methods for my study. Analysis of urine for heavy metals? Analysis of whole blood for selected organic compounds?

08 January 2020 8,531 3 View