What is the standard of care for high risk Gestational Trophoblatic Tumor? What is the role of Actinomycin -D?

More Ganesh Dangal's questions See All

Which is the best wavelength to study aerosol optical depth(AOD) related to climate reseach,which criteria must be adopted in choosing the wavelengh?

We are doing a study on impact of aerosol on precipitation. Which satellite data and which wavelength will be the best. or can some one suggest a criteria to be adopted to choose an instrument...

12 February 2021 6,324 3 View

Let me know whether the DOI issued by the research gate will be accepted by the anna university?

As per the rules and regulation DOI is needed and paper has to be opened in online by the anna university rules let me know whether the published article in some journal and the DOI issued by...

27 November 2020 7,540 2 View

Experiencing Students Anxiety during COVID-19: Who has been getting more anxiety among the college students, boys or girls? Why?

Research based evidence needed

05 October 2020 663 19 View

What are the alternative way to identify the stem cells present in cord blood??

commonly used practices for the identification and characterization of the kind of cell in cord blood other than Flowcytometry and reverse-transcription polymerase chain reaction (RT-PCR).

08 August 2020 6,881 3 View

What is the difference between Hex Dominant and Cut Cell Meshing methods in CFD?

Though both the methods look similar I believe there may be differences in them. What are the disadvantages of cut-cell meshing method and why is not widely used in research in comparison with...

12 July 2020 5,636 3 View

Does anyone have GS-990 DIW EIW water filtration equipment from Advantec Japan?

I tried to contact [email protected] but no response so kindly help me in this regard. We have an Advantec GS-990, it was purchased a long time ago from a Korean Collaboration. Currently,...

16 June 2020 9,890 1 View

What is the difference between anionic and cationic redox probes?

I have done Kinetics study of two different probes namely Fe(CN)63-/4- and Ru(boy)2+ on glassy carbon electrode. I kept the potential between -0.2 to 0.6 and 0.8 to 1.2 respectively. In FeCN when...

25 April 2020 3,364 10 View

Is SIMSCALE software a good to go option for visualizing and understanding academic concepts?

On what scale can SIMSCALE simulation software be helpful for students in their engineering course work comprising CFD ( Computational fluid dynamics ), thermal and structural concepts? Can...

29 March 2020 2,952 3 View

Is the Reference Intensity Ratio of Martensite(7.98) and that of Austenite (10.81), standardized against corundum, constant?

I came across the RIR value of Martensite in a paper, which is 7.98. Similarly for Austenite, which is 10.81. I want to quantify Retained Austenite in my heat treated samples. I am using Reference...

26 February 2020 9,401 2 View

Can a thermoelectric material may have negative lattice thermal conductivity?

I have calculated electronic components of thermal conductivity by wiedmanfranz law. Then the lattice thermal conductivity is derived from it. But some of those values are negative. at the end of...

26 January 2020 1,507 4 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

Is there a powerful system for the security of the systems distributed on IoT systems?

02 March 2021 3,858 10 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

How Relativistic effects is one reason for lanthanide contraction?

The Lanthanide contraction which is the decrease in ionic radii of the elements in the lanthanide series from atomic number 57, lanthanum, to 71, lutetium, is due to poor shielding of the 4f...

01 March 2021 2,272 4 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

How to avoid ulcers in s.c. injected tumors ?

Recently, we have injected s.c. B16F10 tumor cells in BL/6 mice. At around 12-15th day some animals showed ulcerations in tumors , with a big hole in the middle (it looks like a volcano). We have...

01 March 2021 9,938 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Does the circuit modeling for planar monopole antennas using Foster canonical forms give good approximation?

Hi researchers, I am searching for some accurate way to do the circuit modeling of planar CPW-fed monopole antennas. I have gone through the literature where mostly circuit modeling is done using...

28 February 2021 7,016 1 View

For modelling epoxy-based matrices (in composites), which model in ABAQUS is the most suitable, Concrete damaged plasticity or Drucker-Prager model?

I am working on developing a micromechanical FE model for predicting kink-band formation in UD composites. To model matrix plasticity, which model, out of Concrete Damaged Plasticity and...

28 February 2021 5,415 1 View

Shabtai Romano

the choice of treatment is EMA-CO .

Ganesh Dangal

Many thanks Dr Romano but what about single agent like actinomycin D ?

Gamal Abdul Hamid

Dr Ganesh , Actinomycin D is working well in low risk gestational trophoblastic neoplasia. In High risk the protocols EMA-CO and EP-EMA. Also paclitaxel containin regimen (TP/TE) may play a role