A new Alzheimer drug still under study has been found to give a protective effect to prevent dental caries by "increasing dentin".
--What is dentin?
--By what mechanism of action is this Alzheimer drug "increasing dentin"?
Dennis
Dennis Mazur
Hello Dennis and Joachim,
you need no medicine to stimulate pulp cells to build new dentine, they can do that without help. But unfortunately the pulp cells are in the centre of the tooth (Cavum pulpae), while the caries is peripheral.
So the approach of this articile
https://www.researchgate.net/deref/https%3A%2F%2Fwww.nature.com%2Farticles%2Fsrep39654
does not hit the nail.
You can force the tooth to build new dentine in the cavum, it will help a little bit, but you will not be able to close cavities in the dentine or enamel in this manner. Ca (OH)2 is known since a long time to stimulate the proliferation of new dentine (but, of course, IN the pulp), this is not really new.
Best regards,
Rudolf
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