Function of leptin is same or different in physiological and pathological condition (obese)
Open Journal of Immunology, 2014, 4, 42-50
Published Online June 2014 in SciRes. http://www.scirp.org/journal/oji
http://dx.doi.org/10.4236/oji.2014.42006
How to cite this paper: Brito Díaz, B., Marcelino Rodríguez, I., Almeida González, D., Rodríguez Pérez, M.C. and Cabrera de
León, A. (2014) An Overview of Leptin and the Th1/Th2 Balance. Open Journal of Immunology, 4, 42-50.
http://dx.doi.org/10.4236/oji.2014.42006
An Overview of Leptin and the Th1/Th2
Balance
Buenaventura Brito Díaz1, Itahisa Marcelino Rodríguez1, Delia Almeida González1,2,
María del Cristo Rodríguez Pérez1, Antonio Cabrera de León1,3
Leptin is often referred to as an “obesity hormone, a fat hormone or a starvation hormone.” This hormone is predominantly synthesized and secreted by our adipose tissues specifically the white adipose tissue, then it acts on the hypothalamus located in our brain and other peripheral tissues. This hormone signals our body to stop eating for we are already satiated. Elevated adipose leptin and plasma leptin levels are seen in obese patients wherein their body fails to reduce excess adiposity – which indicates a state of leptin resistance.
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