As we know CD4CD28- T Cells behaves like pro-inflammatory cells, so would like to know if this effect correlates with CD8CD28- T cells as well.
Thanks.
Dear Gnaneshwar Jadav
CD8CD28 Can suppress effector T cell function in several experiments as well in Humans. Interfere with regulatory of autoimmune diseases and heart kidney transplants. Pls. find the attached files
https://www.hindawi.com/journals/arthritis/2012/805875/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173691/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC198520/
http://www.nature.com/cmi/journal/v12/n6/full/cmi2014118a.html http://www.ncbi.nlm.nih.gov/pubmed/14523041
http://www.pnas.org/content/104/44/17459.full.pdf
Page 140 in: Richard Blumberg, Markus F. Neurath. 2007. Immune Mechanisms in Inflammatory Bowel Disease Springer Science & Business Media,Pp.248 ISBN 0387337784, 9780387337784
Claudio Ronco, Stefano Chiaramonte, Giuseppe Remuzzi. 2005. Kidney Transplantation: Strategies to Prevent Organ Rejection Karger Medical and Scientific Publishers,Pp. 155. ISBN3805578563,9783805578561
Kurt Blaser.2008.T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases Karger Medical and Scientific Publishers,Pp.225. 3805586280, 9783805586283
Anthony Atala, Robert Lanza, Robert Nerem, James A. Thomson. 2011. Principles of Regenerative Medicine Academic Press,Pp.1472. ISBN0080555950, 9780080555959
https://orbi.ulg.ac.be/bitstream/2268/179694/1/cyclophosphamide.pdf
Hoping this will be helpful
Regards
Prof. Houda Kawas
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