In my experience it ist almost impossible to filter such kind of artifacts and very often the signal saturates. Do you have an example?

Hi Saleh,

As Niels mentioned above this is a very tricky one. Something I had used with neuronexus 16 chn probes and it actually works (partially) is the following:

If we assume that the motion artifact is more or less common for the nearby recording sites but the neural activity is not, then you can subtract the signal from two nearby probes and the common component ie noise will go away.

You can also try with processing by defining the frequency range of the noise, usually low frequencies dominate, and filter them away or even try to apply pca or ica to decontaminate your signal...

Best

Stylianos

Thanks,

I think that PCA or ICA would be useful.

Hi both,

This question is quite interesting to me, as I have the same problem (with one 32-channel probe recording in mice). The motion artifacts interfere with my detection of sharp wave ripples-spectrally the artifacts have more power in the ripple band than real ripples. I can therefore detect sleep ripples, but not wake ripples. In newer recordings, this is not a problem, probably because my surgery technique has improved, but hoping to recover the data from the first two mice. The PCA idea is interesting, I will give that a try. I have attached small screenshots of the motion noise vs. the 'clean' sleep data.

Thanks,

Claire

Hi Claire,

In what aspects did your surgery technique improved?