In fact the fall of platelets is related to our immune defense. It turns out that the lymphocytes (CD 4 and CD 8) to try to combat the virus also end up destroying platelets. Dengue hemorrhagic fever usually affects people who have had other forms of dengue fever (milder) and so the memory cells of our immune system react more strongly generating excess substances to combat the virus and end up affecting also the platelets. This, coupled with the fact that viruses cause fragility of blood capillaries and cause hemorrhagic dengue.
Thrombocytopenia- a disorder relative decrease of thrombocytes, commonly known as platelets, present in the blood. (Ref.wikipedia)
causes can be inherited or acquired
Decreased production due to Dengue fever
Increased destruction due to immune or non-immune reasons
‘Low platelet count doesn’t always mean dengue’
http://timesofindia.indiatimes.com/city/pune/Low-platelet-count-doesnt-always-mean-dengue/articleshow/16998081.cms
Role of platelet transfusion in the management of dengue patients in a tertiary care hospital
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168133/
More details of could be found in "Role of CD61+ cells in thrombocytopenia of dengue patients"(Int J Hematol. 2012 Nov; 96(5): 600–610.
Plasma leakage, dengue produces lots of holes in your blood vessels causing fluids and platelet to sip out.
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