From 1-10uM

The normal physiological concentration of hydrogen peroxide (H₂O₂) in human saliva is generally low, typically in the micromolar (µM) range. This low concentration is due to the presence of various antioxidant systems in saliva that continuously degrade H₂O₂ to maintain oral health and prevent oxidative damage.

Saliva contains enzymes such as salivary peroxidase, which plays a crucial role in the breakdown of H₂O₂. These enzymes help to maintain the balance of reactive oxygen species (ROS) in the oral cavity, ensuring that H₂O₂ levels remain within a range that is not harmful to oral tissues.

While specific baseline values for H₂O₂ in human saliva can vary based on individual health status, diet, and environmental factors, the general consensus is that under normal physiological conditions, H₂O₂ concentrations are maintained at low levels through the action of salivary antioxidants.

It's important to note that external factors, such as the use of hydrogen peroxide-containing oral care products or certain medical conditions, can temporarily elevate H₂O₂ levels in saliva. However, under typical circumstances, the concentration remains within a range that does not pose a risk to oral health.