Currently working on a project and it would be really useful if you could kindly help me with the normal HOMA- % B in normal healthy individuals and during the diagnosis of type 2 diabetes please.
Thank you in advance!
The normal ranges for HOMA-%B and HOMA-IR that I provided are based on general clinical guidelines and may vary depending on the laboratory reference ranges used.
HOMA-%B and HOMA-IR are markers used to assess insulin resistance and beta-cell function in individuals.
HOMA-%B (homeostasis model assessment of beta-cell function) represents the percentage of beta-cell function in relation to a reference individual with normal glucose tolerance. A value of 100% indicates normal beta-cell function.
HOMA-IR (homeostasis model assessment of insulin resistance) represents insulin resistance in the body. Higher HOMA-IR values indicate increased insulin resistance.
The normal range for HOMA-%B varies depending on the laboratory reference range used, but generally, a HOMA-%B value of 80-120% is considered normal. Values below 80% indicate impaired beta-cell function.
For HOMA-IR, a value of less than 2.5 is generally considered normal. Values between 2.5 and 3.8 indicate mild insulin resistance, while values greater than 3.8 indicate moderate to severe insulin resistance
During the diagnosis of type 2 diabetes, HOMA-%B and HOMA-IR levels are typically measured to assess beta-cell function and insulin resistance, respectively. In individuals with type 2 diabetes, HOMA-%B values are often below 50%, indicating impaired beta-cell function. HOMA-IR values are typically elevated, reflecting insulin resistance.
reference :
https://pubmed.ncbi.nlm.nih.gov/33298413/
https://diabetesjournals.org/care/issue/44/Supplement_1
- Badges
- Science topic
- Similar topics
- Phytochemistry
- Extracts