In the literature, they use Dowex 50wx8(H+) to get the free proline derivative from its trifluoroacetate salt, but usually it is obtained from its sodium salt using the same ionic resin.
Thank you for your answer! Perhaps I know what you mean and as what you have said that to substitute the anion usually needs a anion exchange resin. But in my case, I want to obtain the proline derivative from its trifluoroacetate, as usual I should use the anion resin, and I just think so before I did it. However, when I was studying on the references related to the method of obtaining the same compound whicht I was synthesizing, I found they all used the cation exchane resin to gain the target compound from trifluoroacetate. That`s why I asked the mechanism of it which is different from the usual way.
Thank you very much! To elute the proline aqueous ammonia was used in the reference. I think you are right. I am wondering that the remaining trifluoroacetic acid would still stay in the system, or became ammonium salt.
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