I would like to know how does coffee affect our whole system - to be more specific, our central nervous system. I mean, how does coffee stimulate our cells and enhance our performance through making us attentive.
I would like to know its mechanisms that might involve the digestive system, HCL secretion and then cell activation.
I am not sure whether it has a direct effect on activation or does it get absorbed into our body, enter into our blood and then have an impact on stimulating cells.
I would appreciate if somebody has some review papers or some materials that can elucidate this mechanism of our whole system - particularly involving the digestive system, central nervous system and the rest of the system accordingly.
Looking forward to your kind suggestion.
caffeine has wide area of work and available knowledge i have not fully told you but i attached a book chapter of A. smith. this chapter help you to star your study.
ajeet
You will find in the paper "Fluids Hypertension Syndromes and the caffeine intoxication", available free at www.izecksohn.com/leonardo/ .
Kindly see the following RG links.
Article Caffeine and the central nervous system: Mechanisms of actio...
Article Caffeine: Cognitive and Physical Performance Enhancer or Psy...
Caffeine is rapidly and completely absorbed within an hour following ingestion. It is distributed throughout body water and readily crosses cell membranes including the brain. Its primary mechanisms for stimulatory activity appear to be the blocking of adenosine receptors and inhibition of phosphodiesterase. Caffeine hijacks this natural process by mimicking adenosine in the brain. It latches onto the receptors designed for adenosine, pushing them out of the way. As a result, we’re left feeling more alert and awake. The researchers think that by blocking adenosine, caffeine may reduce heart risks since adenosine triggers irregular heartbeats.
https://www.ncbi.nlm.nih.gov/books/NBK223808/
https://www.businessinsider.com/physical-mental-effects-of-caffeine-2017-7#it-makes-us-feel-alert-at-least-for-a-while-2
Also, check the following link:
https://www.nap.edu/read/18607/chapter/7
The main action of caffeine seems to be the constriction of arterial vessels, very similar of the adrenaline effect. But the adrenaline effect finishes in few minutes, and the caffeine`s lasts for many hours. This results in the ischemic lesions of those already ischemic tissues, like osseous, chondrocytes, etc. Meanwhile, there are other many secondary effects which individually variate upon the daily dose, genetic propensity, age, time, etc.
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