Dear Dr Kushal Kumar

If you know the human dose of the drug in ethnomedicinal practices, you can calculate the animal doses according to the surface area caculations given in the following reference.

 G.E. Paget, J.M. Barnes

Evaluation of drug activities pharmacometries

, D.R. Laurence, A.L. Bacharach, Toxicity tests, Volume vol. 1, 1964, Academic Press, London and New York, pp. 135–166

Dear Dr Kushal Kumar

If you know the human dose of the drug in ethnomedicinal practices, you can calculate the animal doses according to the surface area caculations given in the following reference.

 G.E. Paget, J.M. Barnes

Evaluation of drug activities pharmacometries

, D.R. Laurence, A.L. Bacharach, Toxicity tests, Volume vol. 1, 1964, Academic Press, London and New York, pp. 135–166

daily doses in ethnobotanical practice may also refer to Recomended Daily Intake (RDI)

Dear Dr Kaushal 

I think the calculation of dose is a challenging task in the ethomedicinal practice and needs a proper scientific standardization. The traditional healers generally provide a randomized dose depends upon the situation. In my opinion, It is better to find out the dose by some safety and toxicity studies (LD50, ED 50 etc), and if the botanical preparation is well established then you can go for the calculation of the ratio by the proven established dose and the dose given by a folk practitioner, but the chances of errors may be there.