What is the inhibitory concentration of Geldanamycin for yeast?

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Mysore Krishnaiah Sateesh

3.2-12.8 mg/L

See the article

Mycopathologia. 2013 Apr;175(3-4):273-9. doi: 10.1007/s11046-012-9612-1. Epub 2013 Jan 23.

Antifungal activity of geldanamycin alone or in combination with fluconazole against Candida species.

Anubhav Singh Nahar

In candia sc5314 5- 20 micromolar per ml. i suggest you should start from 40 micromolar GDA. However, mic can vary depending upon what method you used. CLSI methodology is highly acceptable. agar based method(YPD, SC) will show high MIC.

Sai Manohar Thota

Thanks a lot Dr. Krishnaiah and Mr.Anubhav for your valuable suggestions.