You can try to do inverse analysis to quantify the uncertainties. ~DM

I would start by qualifying measurement accuracy by measuring variations of observations in a priori stable conditions, then having framed what I would assume to be measurement accuracy I would bin measurements according to measurement accuracy over whole space of operating conditions. Variations of observation parameters in same operating conditions would be flagged uncertainty.

Without understanding the uncertainty (and the variation) you could end up chasing your tail with random noise.

We must understand the "uncertainty" of our experimental values in order to know whether we are observing real effects or random fluctuations. The "uncertainty" is simply the error range of the data. There are many easy formulas to calculate the error (inverse of "Goodness of Fit") in any set of data.

In general, there are aleatory and epistemic uncertainties that need to be differentiated and quantified.