Can same bed temperature be kept for all kinds of tablets or it should be changed? What are the important factors to be considered?
Dear Abhishek;
Bed temperature is not an independent parameter it depends on inlet temperature and spray rate so we can not fix the same bed temperature for all products.Their are so many factors which decides inlet temperature and spray rate like;
1.Coating system: Aqueous/Non aqueous.
2.Hardness of tablet and nature of drug product.
3.Size and surface ( score or embossed ) of Tablet
4.Occupancy in Pan etc.
Dear Abhisek
Tablet bed temperature is important during coating because it bed temp. increase from normal tolerance temperature then tablets coat melt down. Then one tablet attached with another one.
If temperature is below coating drying temperature then coating solution may drain from coating bed.
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