What is the difference between JCR impact factor and Science Citations index impact factor ?

If a journal Impact factor in SCI But no impact factor as per Journal citation reports . Is SCI valid

14 January 2021 325 5 View

What may be the effective strategy to design primers of miRNAs for qRT-PCR?

I designed Primers for miRNAs using mirPrimer algorithm. However when l analysed them by Oligoanalyzer 3.1, it shows Primer-dimer and secondary structure formation. I request your suggestion...

19 September 2020 4,149 3 View

Hello all, what are safe data repository websites?

As many journals expect the researcher to submit the data on the online depository sites? I am unable to locate one?

09 June 2020 6,707 4 View

How can states overcome the catastrophic of COVID 19 and other natural clamitities in this globalised world?

I believe it looks like the 'third world war' is going on where entire world is under lockdown, many have died, many are affected by this Covid 19 catastrophy. Why can not countries findout what...

26 March 2020 8,528 15 View

How to run GUI applications inside Docker Containers?

Actually I developed a gui app using tkinter(Python). But can't display tkinter gui from within docker. Did someone has this problem before ? How can I fix it ? Please suggest me some useful links.

05 March 2020 5,457 3 View

Is IoT future Technology of the World ?

What are the trending Research areas in IoT at Present that need to be more focussed?

21 January 2020 1,994 8 View

Can anyone tell me which antibodies for Neurons, astrocyte and glial cells were used for FACS sorting?

We are looking for antibodies that efficiently label neurons, astrocytes and glial cells from mouse brain through FACS sorting for RNA Seq. We tried various antibodies but it does not work in...

05 December 2019 5,334 2 View

How to do modal analysis of pipe contained with water in ANSYS?

13 October 2019 8,564 4 View

What is more important for a quality of research ? A journal with high impact factor or reputation of a journal ?

I have seen that there are some journal having high impact factor does not have a good reputation in the scientific community. On the other hand there are some journals having good reputation with...

13 September 2019 6,356 8 View

How can liquid substance be given to rats as mg/kg bw dose?

Eugenol (Sigma Aldrich, density = 1.067 g/ml) is in liquid form. I want to administer eugenol in Wistar rats i.p. in various mg/kg bw doses. How can I convert ml into mg dose?

06 May 2019 3,655 2 View

What are the pros and cons for mice versus rats?

Hi Everyone, I am designing a pilot study using rodents to assess the effects of simulated space environments (radiation + altered gravity) on microbiome and immune system. I have limited...

24 February 2021 1,825 3 View

What are the ranges of four diffterent poles of butterworth filter for ECG signal?

Hi, Can anyone please tell me what are the ranges of four different pole orders such as first order, second order, third order and fourth order respectively of butterworth filter for ECG...

23 February 2021 2,554 3 View

What should be the duration of exposure to simulated space environments with Rodents?

Hi, I am currently working on a pilot study to get some data related to the impact of long duration spaceflight to the microbiome and the immune system. I plan to use rats and simulate...

22 February 2021 592 1 View

How can you tell if your organotypic slice culture is healthy ?

I'm working on organotypic cerebellar slice cultures from postnatal rats and I'm not sure how to tell if the slices are healthy at any given point. I know there should be a lot of microglial...

15 February 2021 2,830 2 View

Why daily dexamethasone given to rats fed high fat/fructose/salt cause very high mortality rate?

rats were given daily dexamethasone in drinking water corresponding to 0.5 mg/kg or 2 mg/kg. These rats are simultaneously fed 25% fat, 3% salt in diet and 10% fructose in drinking water but...

15 February 2021 7,634 2 View

How to calculate the sample size required to detect the difference in pharmacokinetics of methotrexate?

I came across with this study here, https://www.clinexprheumatol.org/abstract.asp?a=5066 And this study says: "The sample size calculation was done to compare two different MTX starting dose...

14 February 2021 3,017 3 View

Can anyone suggest a way to dissolve insulin which is for rat/mouse injection?

We are trying to inject insulin to rat or mouse, but the insulin we've got is powder, and there are many ways for dissolve, like in saline, PBS, DMSO, or in Tris-HCl, can anyone give us a...

13 February 2021 8,426 10 View

Should the AUC in a concentration-time graph of a subcutaneous implant be roughly the same for poeple?

I have 2 concentration time curves of a subcut drug implant. the first group has a peak around the 50 day mark where as the second group does not. Both groups received the same implant by the same...

10 February 2021 2,305 3 View

How do I fix tissue rolling while cutting frozen rat brain section with a cryostat?

I am cutting rat brain sections at 20um at -20C. The tissue is cutting nicely out of the O.C.T solution, but I can not get a decent section to adhere to the slide. I have included an image.

09 February 2021 1,345 5 View

Rat Macrophage Markers for Flow Cytometry?

Hello, I'm trying to identify good putative macrophage markers for flow cytometry in rats.

04 February 2021 3,913 4 View