openbabel can be used to add partial charges to molecules using this command:

obabel -i pdb lig.pdb -o mol2 -O lig.mol2 -partialcharges

where can be replaced by any type written in this website (https://open-babel.readthedocs.io/en/latest/Charges/charges.html)

So, what is the difference between these partial charges types? and which one is preferable for MDS of protein-ligand complexes?

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