Hi Fateme,

if the question stems from the need to find a suitable tES intervention, I would suggest to start with the analysis of psychopathological/neurobiological mechanism responsible for the "to-be-treated" phenomenon (i.e., is it related to a decreased activity of a brain structure/network or is it related to certain bands of oscillatory power?).

Although you could compare the duration of tDCS vs tACS aftereffects (e.g., reviewing single or multiple session tES studies), such comparison might not be therapeutically valid given that tDCS and tACS induce qualitatively diverging effect and you would need to consider WHICH of the effects are meaningful for the particular therapeutic intervention (rather than which lasts longer).

On the other hand, both tDCS and tACS are assumed to modulate neuroplasticity, so perhaps this could be set as the common feature, enabling a meaningful comparison to start with.

Best, M.

Thanks dear Martin for your answer

@ Martin Marko

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