What is the difference between GC-ms and LC MS?

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Mohammed I. Rushdi

GC MS for volatile fraction while LC MS you deal with any fraction using suitable solvent systems.

Grzegorz Boczkaj

For your purpose GC is the best solution. Remember to acidify the sample prior to analysis - organic acinds must be in neutral form. Thins about headspace technique.

Regards

Udaya Jayasundara

If your samples are volatile, then you should use GC if not LC. MS is the detection method