What is the difference between blunt-ended dsRNA and dsRNA with overhangs (viral RNA)?

20 January 2014 1 7K Report

It might just be a question of semantics but I would appreciate if somebody could help clarify this. Is the difference (only) the fact that overhang dsRNAs have unpaired nucleotides at the end and blunt-ended dsRNAs have completely paired nucleotides? Is it possible to have 5'triphosphate (ppp) and 3'polyA at the ends of an overhang RNA?

Dacquin Kasumba

Thank you Andrei

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