if you are using a direct extraction method (non-selective extraction), the product can be termed natural extract and free to use without E number. For ingredient design, rheological modification is permitted until the molecular structure is unaltered. GTE and GSE both are permitted as natural ingredients if from a non selective extraction mode and depending on end use, the addition level can be determined. This means the application if dermatological or feed or pharma or neutra, it needs specific quantification that are acceptable to each regulation.

Hope this helps.

 Hi

In EU Grape seed extract included for Feed Additve '' https://www.efsa.europa.eu/en/efsajournal/pub/4476'' . 

As food additive category it is under scrutinization - antioxidant properties etc., - https://www.efsa.europa.eu/sites/default/files/assets/ndaart13ref03.pdf.

Pending approval for antioxidant properties - http://registerofquestions.efsa.europa.eu/roqFrontend/ListOfQuestionsNoLogin?0&panel=NDA&foodsectorarea=26

'' Scientific Opinion on the substantiation of health claims related to oligomeric procyanidins (OPCs) from grape (Vitis vinifera L.) seeds and improvement of visual adaptation to the dark (ID 680) pursuant to Article 13(1) of Regulation (EC) No 1924/2006''  with some limits.

In US, GRAS approved for many applicants and listed in DSHEA.

The reason romery approved b'cz it not novel ingredients and history of use before 1994 in european union. 

All the best

Thank you Mr. Alappatt and Mr. Jayaram for your answers.