Some issues that have prevented large-scale commercialization so far include:

High price (about 50 x more than plant cellulose) because of high-price substrates: sugars and low volumetric yields

Lack of large-scale production capacity

Timely expansion and maintenance of the cell culture for production

(Source: http://en.wikipedia.org/wiki/Microbial_cellulose)

Using bioreactor

There are several ways to produce bacterial cellulose and improve its production including various bioreactor types and medium modification. Agri-waste and food processing waste provide low cost substrates and nutrients. I found these review papers helpful:

Macromol Biosci. 2014 Jan;14(1):10-32. doi: 10.1002/mabi.201300298. Epub 2013 Jul 30. More than meets the eye in bacterial cellulose: biosynthesis, bioprocessing, and applications in advanced fiber composites. Lee KY1, Buldum G, Mantalaris A, Bismarck A.

Cellulose October 2013, Volume 20, Issue 5, pp 2191-2219 Date: 14 Jul 2013 Biosynthesis, production and applications of bacterial cellulose Shin-Ping Lin, Iris Loira Calvar, Jeffrey M. Catchmark, Je-Ruei Liu, Ali Demirci, Kuan-Chen Cheng

Dahman, Y "Production and Utilization of Bacterial Cellulose Nanofibres” Encyclopedia of Nanoscience and Nanotechnology; (2009) 6th edition.

I do not think there is any best way to produce bacterial cellulose.

Thank you for your time and help

It is very simple. If you can achieve uniform oxygen mass transfer in simple static culture under surface aeration, can obtain high amount of bacterial cellulose.

Dear Babaeipour

Thank you for your time for your help.

Regards,

Sherif

I have worked with BC production amd its applications in drug delivery on laboratory scale. We produced BC from few cm wide sheet to 10 cm wide sheet easily.

Dear Prof

Could you please help me ?

I need the best medium composition,shaking or static or other conditions, for production high amount of BC. or if you suggest a proposal of industrial production of BC, I will do that.

Than you for your time and help.

Warm Regards,

Sherif

Dear Sherif,

Thanks for your interest in our research work.

We prepared BC by static method as its produce uniform cellulose.

BR

Munir

Hello,

Anyone would like to tell me that what is the market price rate for ready made Bacterial cellulose?

Hello,

I would appreciate if you help me about the production of highest amount of bacterial cellulose

Regards,

Sherif

Maryam Iqbal ,

Would you like to tell me about the potential application of Bacterial cellulose?

Sherif Moussa Husseiny ,

Assalam o Aliakum,

I was busy and forgot to answer your question. I will discuss the proposal with a friend and supervisor (for permission) and will respond accordingly.

I suggest you to use melass in the medium

Dang Xuan Hoang , Thanks for the suggestion. This will be more for us to understand if you could share some relevant data.

Hi Mr Munair Badshah , this is only my comment on the question. In microbial cellulose production, we usually use appropriate bacterial strain and to reduce the cost of the production we should use byproducts from other industries. This is also beneficial for the environment.

Hi Dang Xuan Hoang , Thanks for you comments and it definitely will help the readers to find some solution.

Dear Munair Badshah ,

Assalamo Aliakum,

I looking forward your reply in due course.

Thank you for your help and time.

Best Regards

Sherif

Dear, Sherif Mousa Husseiny,

Plz help ( I would appreciate if you help me about the production of highest amount of bacterial cellulose ).

Thank you.

Dear Dr. Maryam ,

Up till now , the problem of high production do not solve .

Warm Regards,

Sherif

Assalam o Alaikum Sherif Moussa Husseiny , It high production requires skills and facilities.

Hope you have liked the pictures of BC sheets I have shared.

BR

Munair

Assalam Alaikum,

Thank you for your time and help. BC sheets at bench scale are good results. I still search on the high production (semi pilot ) .

Regards,

Sherif

Hi Mr Munair Badshah@ Munair Badshah , can you please share the pictures of BC sheets with me? Thank you.

Ge Gao , Here I am sharing the pictures of bacterial cellulose.