Exosomes in plasma can be isolated using different method such as greadiatnt centrifugation, Chemical isolation. but these method are so expensive, are there new method for isolated of exosomes in less cost?
There is a range of methods available indeed, the efficiency of six of the most popular has been evaluated in this article Article Quality and efficiency assessment of six extracellular vesic...
Ultracentrifugation will give high purity exosomes in low amounts, while gravity size-exclusion chromatography will yield higher amounts of EVs of lower purity (higher amounts of lipo-proteins)