Platelet-rich plasma (PRP) or platelet concentrate is obtained from the patient and subsequent removal by centrifugation of fresh blood collected using sodium citrate as an anticoagulant at low speed, in order to sediment the erythrocytes and leukocytes and keep the platelets in suspension in plasma. This is then transferred to another tube and is the Platelet Rich Plasma (PRP) . This process allows the concentration of large numbers of platelets in a position to release growth factors in a small volume of plasma.
Scientists have found over 1100 different proteins in platelets , and the most studied is derived growth factor (PDGF ) , transforming growth factor ( ? TGF - ) , epidermal growth factor derived from platelets ( PDEGF ) , the factor vascular endothelial growth factor ( VEGF ) , insulin-like factor 1 growth factor (IGF - 1 ) , fibroblast growth factor ( FGF ) , epidermal growth factor ( EGF ) . All present in platelet-rich plasma (PRP) .
The PRP or Platelet Rich Plasma is injected directly into the damaged area depending on the needs of each patient . The high concentration of platelets - 8 to 10 times the volume of normal blood - catalyzes the growth of new cells and recovery from injury caused by trauma or degenerative processes of tendons, muscles and cartilage.
I suppose PRGF is a distinct entity , apart from PRP or PRF... with a different protocol of preparation... if ne1 can detail me on that and its application... will serve me better.