I am working on a project to classify lung CT images using CNN, and

as I understand, the pixel spacing is distance between the center of each pixel, specified by a numeric pair - adjacent row spacing and adjacent column spacing in mm (this is in 2D space), but because the CT images are 3D, the pixel spacing shows a triple value, and I thought that the second and third value are row pixel spacing and column pixel spacing, but the first value is Z dimension which means slice thickness, I am right or not?

the another question is: as it's known, CT scans has a different slice thickness, if I work on 2D slice of CT, I need to make all slice the same thickness or its only necessary when working on 3D scans?

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