What inflammatory biomarkers should be measured in individuals with non-alcoholic fatty liver disease(NAFLD)?

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Martin Hofmeister

Dear respected Hamidreza Khalounejad,

Perhaps you could consider the high-density lipoprotein cholesterol ratio (MHR) as a NAFLD novel inflammatory biomarker.

Best wishes from Germany,

Martin

Zhao Y, Xia J, He H, Liang S, Zhang H, Gan W. Diagnostic performance of novel inflammatory biomarkers based on ratios of laboratory indicators for nonalcoholic fatty liver disease. Front Endocrinol (Lausanne). 2022;13:981196. https://doi.org/10.3389/fendo.2022.981196

Elwira Kaminska

Hi,

If you are looking for novel biomarkers and have some clinical samples available, you could use proteomics approach. One of the is what Sengenics offers, a discovery platform to screen for autoantibodies to ~1800 antigens involved in rheumatology & infectious diseases, oncology, neurology and endocrinology. Feel free to email me directly if you would like to learn more - [email protected]

There are other technologies for novel biomarker discovery within proteomics, such as Olink - for protein measurements. I hope this helps.

All my best,

Elwira