The medical device is to replace a soft tissue without any load bearings.
Looking for general information and direction to where to look for information on the structural changes of thermoplastic elastomers once they have been implanted (long term)?
Polyurethane is a generic name...... there are dozens, if not hundred types of PU.. so in-vivo stability of PU depends on many factors..
General rule of thumb is polyurethane based on polycarbonate polyols perform better when compared to polyether polyols in-vivo..
Search for BioSpan and Carbosil in google scholar..
hi,
you can have a look at
- the water uptake of your material
- its sensitivity to hydrolysis
- its sensibility to oxidation
the 3 phenomena can lead to changes in mechanical properties
regards
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