Nanoparticles are a new approach to deal with infections caused by multidrug resistance bacteria, to do this function , the size of these particles is very important in the mechanism of action.
To take advantage of unique properties of nanoscale materials and structures, the size, shape and/or surface chemistry of nanoparticles need to be optimized, allowing their functionalities to be tailored for different biomedical applications.
As Amal Talib Al Sa'ady has mentioned, it is necessary to define the application of nanoparticles first. The MDRs may be dealt with at a range of 15-100 nm.
Here's a brief overview on invitro studies against MDRs:
Article Nanoparticles in the Treatment of Infections Caused by Multi...